Simulation of arteriosclerosis in a virtual artery

James E. Kennedy, Clement L. Higginbotham, Pierre Antoine Fourrier, Keith Vaugh

Research output: Contribution to journalArticlepeer-review

Abstract

Finite element analysis (FEA) was developed for the analysis of systems that are geometrically difficult to define, precluding the use of closed form calculations for stress, displacement, etc. This makes FEA a perfect tool for the detailed analysis of biological, specifically biomechanical, systems. This work has focused on the development of a virtual simplified artery using finite element analysis and Visual Basic programming. From the results obtained, important observations were made when analysing the virtual growth of arteriosclerosis process. It was found that the effect of virtual arteriosclerosis, is not life threatening until the virtual artery was within 17% of being closed. Also, it was noted that the elasticity of the virtual artery decreased due to the increased build up of virtual plaque.

Original languageEnglish
Pages (from-to)82-93
Number of pages12
JournalInternational Journal of Medical Engineering and Informatics
Volume2
Issue number1
DOIs
Publication statusPublished - Dec 2010

Keywords

  • Arteriosclerosis
  • Bernoulli equation
  • Biomedical systems
  • FEA
  • Finite element analysis
  • Kinetic energy
  • Plague
  • Soft tissue
  • Virtual artery
  • Wall shear stress
  • Young's modulus

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