TY - JOUR
T1 - Phytocannabinoids - An Overview of the Analytical Methodologies for Detection and Quantification of Therapeutically and Recreationally Relevant Cannabis Compounds
AU - Madden, Olena
AU - Walshe, Jessica
AU - Kishore Patnala, Prem
AU - Barron, John
AU - Meaney, Claire
AU - Murray, Patrick
N1 - Publisher Copyright:
© 2021 Taylor & Francis Group, LLC.
PY - 2023
Y1 - 2023
N2 - The legalization of the cultivation of low Δ9-tetrahydrocannabinol (Δ9-THC) and high cannabidiol (CBD) Cannabis Sativa plants is gaining momentum around the world due to increasing demand for CBD-containing products. In many countries where CBD oils, extracts and CBD-infused foods and beverages are being sold in health shops and supermarkets, appropriate testing of these products is a legal requirement. Normally this involves determining the total Δ9-THC and CBD and their precursor tetrahydrocannabinolic acids (THCA) and cannabidiolic acid (CBDA). As our knowledge of the other relevant cannabinoids expands, it is likely so too will the demand for them as additives in many consumer products ensuring a necessity for quantification methods and protocols for their identification. This paper discusses therapeutically relevant cannabinoids found in Cannabis plant, the applicability and efficiency of existing extraction and analytical techniques as well as the legal requirements for these analyses.
AB - The legalization of the cultivation of low Δ9-tetrahydrocannabinol (Δ9-THC) and high cannabidiol (CBD) Cannabis Sativa plants is gaining momentum around the world due to increasing demand for CBD-containing products. In many countries where CBD oils, extracts and CBD-infused foods and beverages are being sold in health shops and supermarkets, appropriate testing of these products is a legal requirement. Normally this involves determining the total Δ9-THC and CBD and their precursor tetrahydrocannabinolic acids (THCA) and cannabidiolic acid (CBDA). As our knowledge of the other relevant cannabinoids expands, it is likely so too will the demand for them as additives in many consumer products ensuring a necessity for quantification methods and protocols for their identification. This paper discusses therapeutically relevant cannabinoids found in Cannabis plant, the applicability and efficiency of existing extraction and analytical techniques as well as the legal requirements for these analyses.
KW - Analytical techniques
KW - cannabidiol
KW - cannabinoid products
KW - extraction
KW - legal
KW - optimization
KW - phytocannabinoid applications
KW - tetrahydrocannabinol psychoactive activity
KW - therapeutic activity
UR - http://www.scopus.com/inward/record.url?scp=85111868998&partnerID=8YFLogxK
U2 - 10.1080/10408347.2021.1949694
DO - 10.1080/10408347.2021.1949694
M3 - Review article
C2 - 34328047
AN - SCOPUS:85111868998
SN - 1040-8347
VL - 53
SP - 211
EP - 231
JO - Critical Reviews in Analytical Chemistry
JF - Critical Reviews in Analytical Chemistry
IS - 1
ER -