Abstract
Models of human blood vessels have many potential applications as aids in continuing research on new medical devices. The work detailed herein describes the development of a hydrogel material to mimic the mechanical and biological response of a range of human arteries. The developed hydrogels were characterized via swelling studies, differential calorimetry and spectroscopic techniques, while viscoelastic property measurement was investigated primarily using rheological testing methods. A range HEMA/NVP hydrogel materials were successfully developed with properties comparable to a range of arteries, namely, the thoracic and abdominal aorta with storage moduli (G′) varying from 43kPa to 64kPa depending on the formulation. This paper also describes the construction of a mathematical model for the viscoelastic properties of these materials, representing the time-dependent behaviour of the simulated areterial material when subjected to loading and unloading phenomena.
Original language | English |
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Pages | 1859-1864 |
Number of pages | 6 |
Publication status | Published - 2014 |
Event | 72nd Annual Technical Conference of the Society of Plastics Engineers: The Plastics Conference, ANTEC 2014 - Las Vegas, United States Duration: 28 Apr 2014 → 30 Apr 2014 |
Conference
Conference | 72nd Annual Technical Conference of the Society of Plastics Engineers: The Plastics Conference, ANTEC 2014 |
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Country/Territory | United States |
City | Las Vegas |
Period | 28/04/14 → 30/04/14 |
Keywords
- Arterial modeling
- Biomedical
- Hydrogel
- Medical device
- Medical polymers
- Viscoelasticity