Gastrointestinal cancer

Patricia M. Heavey, Ian R. Rowland

Research output: Contribution to journalReview articlepeer-review

73 Citations (Scopus)

Abstract

A combination of both environmental and genetic factors contributes to the vast majority of human cancers and in particular cancers of the gastrointestinal tract, including the stomach, colon and rectum. The mechanisms associated with cancer causation or prevention are largely unknown and the subject of much research. Many of these mechanisms implicate the metabolic activities of the bacterial flora normally resident in the gastrointestinal tract. This paper examines both the detrimental and beneficial consequences of bacterial activity of the gastrointestinal tract, focusing in particular on the stomach and large intestine.

Original languageEnglish
Pages (from-to)323-336
Number of pages14
JournalBailliere's Best Practice and Research in Clinical Gastroenterology
Volume18
Issue number2
DOIs
Publication statusPublished - Apr 2004

Keywords

  • Colorectal cancer
  • Gastrointestinal cancer
  • Helicobacter pylori
  • Microflora

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